MM120, a pharmaceutical form of LSD, shown to reduce anxiety symptoms (2025) (sciencedaily.com)

by carlos-menezes 106 comments 104 points
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106 comments

[−] analog8374 61d ago
"Today a young man on acid realized that all matter is merely energy condensed to a slow vibration, that we are all one consciousness experiencing itself subjectively, there is no such thing as death, life is only a dream, and we are the imagination of ourselves. Here's Tom with the weather."

-Bill Hicks

[−] thin_carapace 61d ago
today an evolved monkey realized that the evolution of intelligence via genetic algorithms doesnt line up that well with the scientific trajectory of existence since the big bang , he then realized that his perception of existence would be exactly equivalent to that of a brain in a jar , his final realization was that all realizations are epheremal regardless as to how convincing or conclusive they may seem
[−] butlike 61d ago
Hell yeah man. Momentary lapse.
[−] Ylpertnodi 61d ago
I can trip to that.
[−] mrroryflint 61d ago
Thanks for reminding me of this. One of the all time greats.
[−] phishin 61d ago
Tool.
[−] throwaway12pol 61d ago
Unfortunately, I will probably never be able to try that for my GAD even if they confirm the positive effects due to stigma surrounding psychoactive drugs! Yay!
[−] steve-atx-7600 61d ago
I’d be afraid of a treatment like this where you’re sort of different after one treatment. From experience taking ssris, I took one one that worked so well that I had to stop taking it because it removed stress to the extent that I wouldn’t get to class on time or get my homework done before deadlines. Eventually I found a medicine that worked for me. But, if there’s a “before” vs “after” one shot treatment, you have to hope the new you is the one you want assuming you could be stuck there permanently.
[−] simulator5g 61d ago
This will be like legal weed. Assuming it isn't already, the pharma bean counters will turn it into something awful.
[−] OutOfHere 61d ago
Of course they want to repackage a cheaply synthesized substance at 100-1000x the costs even though the original likely works just as well. That's pharma for you.
[−] tim-projects 61d ago
I'd argue that the results might not be from the drugs but from the fact that they were heavily monitored by other humans.

It's not the drugs that people with high anxiety need, it's people giving them attention and caring for them.

These experiments need a control where they just take the drug and they don't have medical staff around.

[−] HostingSift 60d ago
The psilocybin data tells a similar story. One or two sessions outperforming months of conventional meds. The fact that both LSD and psilocybin work on neuroplasticity probably isn't a coincidence. Hope regulators don't drag their feet on this for another decade.
[−] rdtsc 61d ago

> It's usually treated with medications like Zoloft and Paxil that boost and stabilize the neurotransmitter serotonin, leading to reduced anxiety and enhanced emotional well-being

How do figure the boost and stabilize part for a patient? Do they take samples of neurotransmitters in the spinal fluid before and after and looking for neurotransmitter concentrations?

[−] kykat 61d ago
It seems like every few weeks there's an article on how drugs are amazing hitting the front-page.
[−] kunley 61d ago
It is tragically funny to consider linking quietness of mind with LSD. It is everything but quiet
[−] butlike 61d ago
At the risk of sounding like an imbecile, can I ask why LSD-25 can't be the pharmaceutical form of LSD?
[−] khelavastr 61d ago
This reflects a longstanding...essentially conspiracy...to suppress attention to 5HT2A-based neural regulation because it sheds such poor light on SSRIs
[−] snvzz 60d ago
Why can we not just get plain LSD?

I have never heard a reasonable argument.

[−] _s_a_m_ 60d ago
how about treating the cause for the anxiety?
[−] Rygian 61d ago
The "surprising way" is by using a derivate of LSD.

I'd argue that the surprise is rather on this: "In clinical trials, a single dose significantly outperformed standard treatments, offering hope to those who have found little relief elsewhere."

[−] dopesoap 59d ago
Just from personal experience I met a bunch of people who did to many psychedelics and became ego maniacs . I also had my first panic attack on acid. Also read about weird therapists taking advantage of people on psychedelics during therapy. I'm a believer in the use of psychedelic therapy but there really needs to be good protocols in place to protect patients who are very vulnerable. I really wish I could go back in time and see the Czech psychedelic clinic it sounded really cool.
[−] tug2024 61d ago
[dead]
[−] the-golden-one 61d ago
Clickbait